Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432703 | 0.91 | KDM4E (0.44) | KDM4EHSD17B10CASP1CACNA1BKMT2A | |
| SCHEMBL9433915 | 0.90 | KDM4E (0.46) | KDM4EHSD17B10CASP1CACNA1BKMT2A | |
| SCHEMBL9434410 | 0.90 | CACNA1B (0.45) | KDM4EHSD17B10CASP1CACNA1BKMT2A | |
| SCHEMBL9434308 | 0.90 | KDM4E (0.43) | KDM4EHSD17B10CASP1CACNA1BKMT2A | |
| SCHEMBL9434033 | 0.88 | KDM4E (0.42) | KDM4EHSD17B10CASP1CACNA1BKMT2A | |
| SCHEMBL9433811 | 0.88 | KDM4E (0.47) | KDM4EHSD17B10CASP1CACNA1BALDH1A1 | |
| SCHEMBL9433376 | 0.87 | KDM4E (0.44) | KDM4EHSD17B10CASP1CACNA1BKMT2A | |
| SCHEMBL9434343 | 0.87 | KDM4E (0.64) | KDM4EHSD17B10CASP1CACNA1BKMT2A | |
| SCHEMBL9433666 | 0.87 | CACNA1B (0.50) | KDM4EHSD17B10CASP1CACNA1B | |
| SCHEMBL9434438 | 0.84 | USP2 (0.46) | KDM4EHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |