Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434483 | 0.98 | EPHX1 (0.55) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA | |
| SCHEMBL9433605 | 0.98 | EPHX1 (0.55) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA | |
| SCHEMBL5701154 | 0.98 | EPHX1 (0.55) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA | |
| SCHEMBL9434500 | 0.98 | EPHX1 (0.55) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA | |
| SCHEMBL9433763 | 0.98 | EPHX1 (0.55) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA | |
| SCHEMBL5701151 | 0.98 | EPHX1 (0.55) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA | |
| SCHEMBL12490812 | 0.94 | EPHX1 (0.47) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA | |
| SCHEMBL9179050 | 0.94 | EPHX1 (0.47) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA | |
| SCHEMBL19066280 | 0.86 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA | |
| SCHEMBL19066279 | 0.86 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2EPHX2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |
| US-4874773-A | HYPOTENSIVE AGENTS, VASODILATORS | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1989-10-17 | — | — | US | disclosed |
| EP-0220653-A2 | 3-Aminocarbonyl-1,4-dihydropyridine-5-carboxylic acid compounds, process for preparation and use thereof, and pharmaceutical composition containing the same | Nippon Shoji Kabushiki Kaisha (JP) | 1987-05-06 | — | — | EP | disclosed |