Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547744 | 1.00 | RARB (0.67) | RARBALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9236995 | 1.00 | RARB (0.67) | RARBALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9238763 | 1.00 | RARB (0.67) | RARBALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10548487 | 1.00 | RARB (0.67) | RARBALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9236481 | 1.00 | RARB (0.67) | RARBALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10552555 | 1.00 | RARB (0.67) | RARBALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10545136 | 0.99 | RARB (0.64) | RARBALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10547849 | 0.95 | RARB (0.59) | RARBALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10545284 | 0.90 | RARB (0.51) | RARBALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10528745 | 0.87 | RARB (0.62) | RARBALDH1A1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279762-A | High speed switching | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5064566-A | Chirally tilted, pyrimidines, pyridines, or pyrazines, stability | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-12 | — | — | US | disclosed |
| US-4834904-A | FERROELECTRIC LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-30 | — | — | US | disclosed |