Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951782 | 0.92 | ERN1 (0.58) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL172664 | 0.92 | ERN1 (0.58) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL8958284 | 0.90 | ERN1 (0.56) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL11407468 | 0.90 | ERN1 (0.56) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL20339320 | 0.90 | ERN1 (0.56) | ERN1KDM4ELMNAMAPTHTT | |
| Phenol SCHEMBL6130969 | 0.89 | TRIM24 (0.48) | ERN1KDM4ELMNAMAPTHTT | |
| Hydrazine SCHEMBL28566747 | 0.88 | ERN1 (0.54) | ERN1KDM4ELMNAMAPTHTT | |
| Catechol SCHEMBL28758914 | 0.85 | TRIM24 (0.57) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL29121131 | 0.85 | ERN1 (0.50) | ERN1KDM4ELMNAMAPTHTT | |
| Alcohol SCHEMBL29234906 | 0.85 | ERN1 (0.50) | ERN1KDM4ELMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011369-A1 | ANTIHYPERTENSIVE 5-[(IMIDAZO[4,5-b]PYRIDIN-3-YL)METHYL]BENZOFURAN DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-05-26 | — | — | WO | disclosed |
| EP-0559724-A1 | BENZOFURAN AND BENZTHIOPHENE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-09-15 | — | — | EP | disclosed |