Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435104 | 1.00 | KDM4E (0.60) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9435116 | 1.00 | KDM4E (0.60) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9082297 | 0.94 | KDM4E (0.62) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9082033 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9082812 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9082272 | 0.88 | KDM4E (0.54) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL10621190 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL10621194 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL10623453 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9084858 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279762-A | High speed switching | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |
| EP-0220296-B1 | SMECTIC LIQUID CRYSTALLINE PHASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-5064566-A | Chirally tilted, pyrimidines, pyridines, or pyrazines, stability | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-12 | — | — | US | disclosed |