Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL28395678 | 0.96 | TP53 (0.79) | TP53TSHRSLC7A5 | |
| Lactic Acid SCHEMBL28395677 | 0.96 | TP53 (0.79) | TP53TSHRSLC7A5 | |
| Lactic Acid SCHEMBL1412661 | 0.92 | TP53 (1.00) | TP53TSHRSLC7A5ALDH1A1LMNA | |
| Lactic Acid SCHEMBL9066423 | 0.92 | TP53 (1.00) | TP53TSHRSLC7A5ALDH1A1LMNA | |
| Lactic Acid SCHEMBL5189465 | 0.92 | TP53 (1.00) | TP53TSHRSLC7A5ALDH1A1LMNA | |
| Lactic Acid SCHEMBL180386 | 0.92 | TP53 (1.00) | TP53TSHRSLC7A5ALDH1A1LMNA | |
| D-Lactic Acid SCHEMBL14947 | 0.92 | — | — | |
| L-Lactic Acid SCHEMBL16958 | 0.92 | — | — | |
| Lactic Acid SCHEMBL9066424 | 0.92 | — | — | |
| L-Lactic Acid SCHEMBL13165963 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237611-A1 | BINDER COMPOSITIONS | OrganoClick AB (SE) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022139670-A1 | BINDER COMPOSITIONS | ORGANOCLICK AB (SE) | 2022-06-30 | — | — | WO | disclosed |
| US-20140158942-A1 | WATER-GAS SHIFT CATALYST | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2014-06-12 | — | — | US | disclosed |
| WO-2012168690-A1 | WATER-GAS SHIFT CATALYST | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-12-13 | — | — | WO | disclosed |
| CN-102014953-A | Influenza immunogenic compositions | BIOLOG MIMETICS INC | 2011-04-13 | — | — | CN | disclosed |
| CN-1134539-C | Thrombopoietin | ��Ĭɭ�����ѧ����˾ | 2004-01-14 | — | — | CN | disclosed |
| CN-1141061-A | Thrombopoietin | GENENTECH INC (US) | 1997-01-22 | — | — | CN | disclosed |
| EP-0375658-B1 | Quinoline derivatives and processes for preparation thereof | DAINIPPON PHARMACEUTICAL CO (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0312085-B1 | NOVEL QUINOLINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND ANTIBACTERIAL AGENT CONTAINING THEM | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-5164392-A | Active against streptococci and staphylococci | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5013841-A | Oxo quinoline derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0375658-A1 | Quinoline derivatives and processes for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0312085-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-04-19 | — | — | EP | disclosed |
| EP-0221463-A2 | Quinoline derivatives and processes for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-05-13 | — | — | EP | disclosed |