Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10514639 | 0.91 | PPARG (0.50) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL9573697 | 0.91 | PPARG (0.47) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL10515170 | 0.87 | PPARG (0.48) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL9573705 | 0.86 | PPARG (0.41) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL9573683 | 0.85 | PPARG (0.42) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL9573694 | 0.85 | PPARG (0.42) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL13846702 | 0.85 | PPARG (0.59) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL9573682 | 0.85 | PPARG (0.42) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL9573700 | 0.84 | PPARG (0.41) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL377496 | 0.82 | FFAR1 (0.43) | PPARGFFAR1ALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559571-A1 | Thiazolidine-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-09-08 | — | — | EP | claimed |
| JP-6009629-A | — | — | None | — | — | JP | disclosed |
| JP-H069629-A | NEW 2,4-THIAZOLIDINEDIONE COMPOUND | ADIR | 1994-01-18 | — | — | JP | disclosed |
| EP-0559571-A1 | Thiazolidine-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-09-08 | — | — | EP | disclosed |