SCHEMBL9436745

SCHEMBL9436745

CC/C=C(\C(=O)O)N(C)C.CCCCCCCCCCCCCCCCBr

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.41
CES2 O00748 3/20 0.35
CES1 P23141 3/20 0.35
GPR84 Q9NQS5 7/20 0.34
PPARG P37231 7/20 0.34
PPARD Q03181 7/20 0.34
PPARA Q07869 7/20 0.34
HDAC11 Q96DB2 5/20 0.34
TSHR P16473 4/20 0.34
PTPN1 P18031 3/20 0.34
ALDH1A1 P00352 2/20 0.34
TLR2 O60603 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
FABP4 P15090 2/20 0.34
SLC22A6 Q4U2R8 1/20 0.34
SLC22A8 Q8TCC7 1/20 0.34
MEN1 O00255 1/20 0.34
ESR1 P03372 1/20 0.34
ALOX15 P16050 1/20 0.34
PDE4A P27815 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromomethane SCHEMBL7095814 0.82 GRIK1 (0.34)
SCHEMBL119131 0.82 GRIK1 (0.36) EP300ALDH1A1
SCHEMBL1531389 0.82 GRIK1 (0.36) EP300ALDH1A1
Hydrochloric Acid SCHEMBL1155809 0.80 GRIK1 (0.35) EP300ALDH1A1
SCHEMBL5083255 0.79 EP300 (0.60) EP300PPARGPPARDPPARAPTPN1
SCHEMBL8849620 0.79 EP300 (0.60) EP300PPARGPPARDPPARAPTPN1
SCHEMBL8850177 0.79 EP300 (0.60) EP300PPARGPPARDPPARAPTPN1
Acetic Acid SCHEMBL11512956 0.78 GRIK1 (0.34)
Chloromethane SCHEMBL124967 0.78 GRIK1 (0.34) TSHRALDH1A1
SCHEMBL5083310 0.77 EP300 (0.57) EP300PPARGPPARDPPARAPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5314627-A Papermaking NALCO CHEMICAL COMPANY (US) 1994-05-24 US claimed
US-5292793-A Copolymer of acrylamide and a quaternized dimethylaminoethyl acrylate NALCO CHEMICAL COMPANY (US) 1994-03-08 US claimed
US-5314627-A Papermaking NALCO CHEMICAL COMPANY (US) 1994-05-24 US disclosed
US-5292793-A Copolymer of acrylamide and a quaternized dimethylaminoethyl acrylate NALCO CHEMICAL COMPANY (US) 1994-03-08 US disclosed