Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GGT1 | P19440 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436991 | 0.95 | KDM4E (0.57) | KDM4EHSD17B10HPGDALDH1A1HMGB1 | |
| SCHEMBL28064330 | 0.93 | KDM4E (0.59) | KDM4EHSD17B10HPGDALDH1A1HMGB1 | |
| SCHEMBL15441430 | 0.85 | KDM4E (0.64) | KDM4EHSD17B10HPGDALDH1A1HMGB1 | |
| Ammonia Solution, Strong SCHEMBL515321 | 0.84 | KDM4E (0.62) | KDM4EHSD17B10HPGDALDH1A1HMGB1 | |
| SCHEMBL12256164 | 0.83 | KDM4E (0.61) | KDM4EHSD17B10HPGDALDH1A1HMGB1 | |
| SCHEMBL14680714 | 0.83 | KDM4E (0.61) | KDM4EHSD17B10HPGDALDH1A1HMGB1 | |
| SCHEMBL1914531 | 0.83 | KDM4E (0.66) | KDM4EHSD17B10HPGDALDH1A1HMGB1 | |
| SCHEMBL12446771 | 0.83 | KDM4E (0.61) | KDM4EHSD17B10HPGDALDH1A1HMGB1 | |
| SCHEMBL7687512 | 0.83 | KDM4E (0.61) | KDM4EHSD17B10HPGDALDH1A1HMGB1 | |
| SCHEMBL12715457 | 0.81 | KDM4E (0.64) | KDM4EHSD17B10HPGDALDH1A1HMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5282995-A | Composition for removing an alkaline earth metal sulfate scale | MOBIL OIL CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |