Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 3/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15291862 | 0.89 | HPGD (0.59) | HPGDTSHRDPP4PDE4APDE4B | |
| Nebracetam SCHEMBL195354 | 0.88 | HPGD (0.60) | HPGDTSHRDPP4PDE4APDE4B | |
| SCHEMBL7436181 | 0.83 | HPGD (0.62) | HPGDTSHRDPP4PDE4APDE4B | |
| SCHEMBL9456344 | 0.83 | HPGD (0.62) | HPGDTSHRDPP4PDE4APDE4B | |
| SCHEMBL13036597 | 0.81 | HPGD (0.60) | HPGDTSHRDPP4PDE4APDE4B | |
| SCHEMBL3240700 | 0.81 | HPGD (0.60) | HPGDTSHRDPP4PDE4APDE4B | |
| SCHEMBL3124428 | 0.81 | HPGD (0.60) | HPGDTSHRDPP4PDE4APDE4B | |
| SCHEMBL20722377 | 0.81 | HPGD (0.60) | HPGDTSHRDPP4PDE4APDE4B | |
| SCHEMBL21704253 | 0.81 | HPGD (0.60) | HPGDTSHRDPP4PDE4APDE4B | |
| Nebracetam SCHEMBL678462 | 0.79 | HPGD (0.51) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281612-A | Naphthyridine antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-4931435-A | TRICYCLIC ANTIDEPRESSANT WITH BENZYLPYRROLIDINONE; SIDE EFFECT REDUCTION | BOEHRINGER INGELHEIM KG (DE) | 1990-06-05 | — | — | US | disclosed |