Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457439 | 1.00 | DPP4 (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL25274064 | 0.94 | DPP4 (0.64) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9116420 | 0.94 | DPP4 (0.64) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL16212854 | 0.94 | DPP4 (0.60) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL10512529 | 0.93 | DPP4 (0.63) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9734972 | 0.91 | DPP4 (0.64) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL25218484 | 0.91 | DPP4 (0.64) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9243986 | 0.89 | DPP4 (0.56) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9437340 | 0.87 | DPP4 (0.58) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9437323 | 0.87 | DPP4 (0.58) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281612-A | Naphthyridine antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1994-01-25 | — | — | US | claimed |
| US-5258528-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1993-11-02 | — | — | US | disclosed |