Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9438765 | 1.00 | ACE (0.66) | ACEMEN1KMT2ALMNAUSP2 | |
| SCHEMBL9438771 | 1.00 | ACE (0.66) | ACEMEN1KMT2ALMNAUSP2 | |
| SCHEMBL9439356 | 0.92 | ACE (0.79) | ACEMEN1KMT2ALMNAUSP2 | |
| SCHEMBL9439369 | 0.92 | ACE (0.79) | ACEMEN1KMT2ALMNAUSP2 | |
| SCHEMBL9439364 | 0.92 | ACE (0.79) | ACEMEN1KMT2ALMNAUSP2 | |
| SCHEMBL9438784 | 0.89 | ACE (0.54) | ACEMEN1KMT2ALMNAUSP2 | |
| SCHEMBL9438798 | 0.89 | ACE (0.54) | ACEMEN1KMT2ALMNAUSP2 | |
| SCHEMBL9438791 | 0.89 | ACE (0.54) | ACEMEN1KMT2ALMNAUSP2 | |
| SCHEMBL683131 | 0.88 | ACE (0.84) | ACEMEN1KMT2ALMNAUSP2 | |
| SCHEMBL9438986 | 0.88 | ACE (0.84) | ACEMEN1KMT2ALMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348944-A | Hypotensive agents | SCHERING CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0050800-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | disclosed |