Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439200 | 1.00 | ACE (0.65) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL9439082 | 0.92 | ACE (0.76) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10822013 | 0.92 | ACE (0.76) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10822014 | 0.92 | ACE (0.76) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10521410 | 0.92 | ACE (0.76) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10521405 | 0.92 | ACE (0.76) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL9439087 | 0.92 | ACE (0.76) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| Hydrochloric Acid SCHEMBL10520208 | 0.91 | ACE (0.75) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| Hydrochloric Acid SCHEMBL9438960 | 0.91 | ACE (0.75) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL7324433 | 0.87 | ACE (0.84) | ACELMNASMN1; SMN2ABCB11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348944-A | Hypotensive agents | SCHERING CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0050800-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | disclosed |