Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.65 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 4/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20212771 | 0.95 | HSD17B3 (0.59) | HSD17B3GSK3BMMP2MMP12HTR7 | |
| SCHEMBL8466864 | 0.93 | HSD17B3 (0.62) | HSD17B3GSK3BMMP2MMP12HTR7 | |
| SCHEMBL13410726 | 0.89 | HSD17B3 (0.57) | HSD17B3GSK3BMMP2MMP12HTR7 | |
| SCHEMBL29178597 | 0.89 | HSD17B3 (0.57) | HSD17B3GSK3BMMP2MMP12HTR7 | |
| SCHEMBL14282470 | 0.86 | HSD17B3 (0.69) | HSD17B3MMP2MMP12HTR7HRH2 | |
| SCHEMBL14275200 | 0.86 | GSK3B (0.61) | HSD17B3GSK3BHTR7HRH1STS | |
| SCHEMBL13085847 | 0.86 | HSD17B3 (0.85) | HSD17B3HTR7STSTHRATHRB | |
| SCHEMBL13085794 | 0.86 | HSD17B3 (0.85) | HSD17B3HTR7STSTHRATHRB | |
| SCHEMBL18753070 | 0.84 | HSD17B3 (0.84) | HSD17B3HTR7STSRAB9ATHRA | |
| SCHEMBL19707549 | 0.81 | GSK3B (0.59) | HSD17B3GSK3BTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341686-B1 | Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements | JAPAN ENERGY CORP (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5137653-A | Alkanoyl ester compounds and their intermediates and method of producing the same | NIPPON MINING CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0311692-B1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5098602-A | Aromatic ester derivatives and fluorophenol ketones | NIPPON MINING CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0341686-A2 | Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements | JAPAN ENERGY CORPORATION (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0311692-A1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1989-04-19 | — | — | EP | disclosed |