Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440286 | 1.00 | PTPN11 (0.43) | PTPN11PPARDRARBRARATHRA | |
| SCHEMBL9224274 | 1.00 | PTPN11 (0.43) | PTPN11PPARDRARBRARATHRA | |
| SCHEMBL9218434 | 1.00 | PTPN11 (0.43) | PTPN11PPARDRARBRARATHRA | |
| SCHEMBL9647578 | 0.92 | PTPN11 (0.44) | PTPN11PPARDRARBRARATHRA | |
| SCHEMBL9225952 | 0.92 | RARB (0.46) | PTPN11RARBRARANFKB1NFKB2 | |
| SCHEMBL9647550 | 0.92 | PTPN11 (0.44) | PTPN11PPARDRARBRARATHRA | |
| SCHEMBL9225424 | 0.92 | RARB (0.46) | PTPN11RARBRARANFKB1NFKB2 | |
| SCHEMBL7754291 | 0.90 | RARB (0.49) | PTPN11RARBRARANFKB1NFKB2 | |
| SCHEMBL7755117 | 0.89 | RARB (0.43) | PTPN11RARBRARANFKB1NFKB2 | |
| SCHEMBL7755306 | 0.89 | RARB (0.43) | PTPN11RARBRARANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328641-A | Naphthalene ester derivatives with trifluoromethyl groups | SHOWA SHELL SEKIYU KABUSHIKI KAISHA | 1994-07-12 | — | — | US | disclosed |
| US-5207947-A | Trifluoroalkyl diaryl triesters; antiferroelectricity; electrooptics | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |