SCHEMBL9440532

SCHEMBL9440532

COCCOCC(O)CCl

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
USP2 O75604 1/20 0.35
POLB P06746 1/20 0.35
HTT P42858 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535158 0.88 CA1 (0.41) HSD17B10ALDH1A1KDM4EUSP2HTT
SCHEMBL7901287 0.85 HSD17B10 (0.44) HSD17B10ALDH1A1KDM4EUSP2POLB
SCHEMBL9447829 0.85 CA1 (0.39) HSD17B10ALDH1A1KDM4EUSP2HTT
SCHEMBL9447834 0.85 CA1 (0.39) HSD17B10ALDH1A1KDM4EUSP2HTT
SCHEMBL6989580 0.83 HSD17B10 (0.42) HSD17B10ALDH1A1KDM4EUSP2POLB
SCHEMBL27220429 0.83 HSD17B10 (0.42) HSD17B10ALDH1A1KDM4EUSP2POLB
SCHEMBL8263940 0.83 HSD17B10 (0.42) HSD17B10ALDH1A1KDM4EUSP2POLB
SCHEMBL9999939 0.83 HSD17B10 (0.42) HSD17B10ALDH1A1KDM4EUSP2POLB
SCHEMBL6305964 0.83
SCHEMBL12516048 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4477687-B1 IMMUNOLOGICALLY INACTIVE POLY(ETHYLENE GLYCOL) POLYMER DERIVATIVES AND BIOCONJUGATES THEREOF FOR USE AS ALTERNATIVE IN PEGYLATED THERAPEUTICS, PROCESSES FOR THEIR PREPARATION AND THEIR USE UNIV MAINZ JOHANNES GUTENBERG (DE) 2025-12-17 EP disclosed
EP-4477687-A1 IMMUNOLOGICALLY INACTIVE POLY(ETHYLENE GLYCOL) POLYMER DERIVATIVES AND BIOCONJUGATES THEREOF FOR USE AS ALTERNATIVE IN PEGYLATED THERAPEUTICS, PROCESSES FOR THEIR PREPARATION AND THEIR USE Johannes Gutenberg-Universität Mainz (DE) 2024-12-18 EP disclosed
EP-0294847-B1 Fluorine-containing nitroazole derivatives and radiosensitizer comprising the same UNIV KYOTO (JP) 1994-02-16 EP disclosed
US-4927941-A Fluorine-containing nitroazole derivatives and radiosensitizer comprising the same Yasunori Nishijima & Daikin Industries Ltd. (JP) 1990-05-22 US disclosed
EP-0294847-A1 Fluorine-containing nitroazole derivatives and radiosensitizer comprising the same KYOTO UNIVERSITY (JP) 1988-12-14 EP disclosed