Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | EYA2 | O00167 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878685 | 0.89 | TDP1 (0.52) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL14357548 | 0.85 | CA1 (0.48) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL19663826 | 0.85 | CA1 (0.70) | CA1CA2CA4CA12CA9 | |
| Pentetic Acid SCHEMBL10361749 | 0.83 | TDP1 (0.60) | TDP1KDM4ELMNACHRM2ADRA2A | |
| Pentetic Acid SCHEMBL9440537 | 0.81 | TDP1 (0.88) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL8425241 | 0.81 | MAPT (0.48) | TDP1KDM4ELMNACHRM2ADRA2A | |
| Pentetic Acid SCHEMBL17138 | 0.81 | TDP1 (1.00) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL137691 | 0.81 | TDP1 (1.00) | TDP1KDM4ELMNACHRM2ADRA2A | |
| Pentetic Acid SCHEMBL2468143 | 0.81 | TDP1 (1.00) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL8866720 | 0.81 | TDP1 (1.00) | TDP1KDM4ELMNACHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353295-B1 | NOVEL AND IMPROVED ANTIBODIES FOR SITE SPECIFIC ATTACHMENT OF COMPOUNDS | CYTOGEN CORP (US) | 1994-04-06 | — | — | EP | claimed |
| EP-0173629-B1 | ANTIBODY-METAL ION COMPLEXES | CYTOGEN CORPORATION (US) | 1992-06-10 | — | — | EP | claimed |
| EP-0382796-A4 | METHOD FOR THE PREPARATION OF ANTIBODY-FRAGMENT CONJUGATES | — | 1991-08-28 | — | — | EP | claimed |
| EP-0382796-A1 | METHOD FOR THE PREPARATION OF ANTIBODY-FRAGMENT CONJUGATES | CYTOGEN CORPORATION (US) | 1990-08-22 | — | — | EP | claimed |
| EP-0353295-A4 | NOVEL AND IMPROVED ANTIBODIES FOR SITE SPECIFIC ATTACHMENT OF COMPOUNDS. | CYTOGEN CORP (US) | 1990-06-26 | — | — | EP | claimed |
| US-4937183-A | Therapy, diagnostis immunology | CYTOGEN CORPORATION (US) | 1990-06-26 | — | — | US | claimed |
| EP-0353295-A1 | NOVEL AND IMPROVED ANTIBODIES FOR SITE SPECIFIC ATTACHMENT OF COMPOUNDS. | CYTOGEN CORP (US) | 1990-02-07 | — | — | EP | claimed |
| WO-1989007269-A1 | METHOD FOR THE PREPARATION OF ANTIBODY-FRAGMENT CONJUGATES | CYTOGEN CORPORATION (US) | 1989-08-10 | — | — | WO | claimed |
| WO-1989007114-A1 | NOVEL AND IMPROVED ANTIBODIES FOR SITE SPECIFIC ATTACHMENT OF COMPOUNDS | CYTOGEN CORPORATION (US) | 1989-08-10 | — | — | WO | claimed |
| US-4741900-A | Antibody-metal ion complexes | CYTOGEN CORPORATION (US) | 1988-05-03 | — | — | US | claimed |
| WO-1986001410-A1 | ANTIBODY-METAL ION COMPLEXES | CYTOGEN CORPORATION (US) | 1986-03-13 | — | — | WO | claimed |
| EP-0173629-A1 | Antibody-metal ion complexes | CYTOGEN CORPORATION (US) | 1986-03-05 | — | — | EP | claimed |
| EP-0173629-B1 | ANTIBODY-METAL ION COMPLEXES | CYTOGEN CORPORATION (US) | 1992-06-10 | — | — | EP | disclosed |
| US-4741900-A | Antibody-metal ion complexes | CYTOGEN CORPORATION (US) | 1988-05-03 | — | — | US | disclosed |
| EP-0257940-A2 | A method of analyzing high molecular weight dispersants in motor oils | The Lubrizol Corporation (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0119675-B1 | HYDROCARBYL-SUBSTITUTED MONO AND BIS SUCCINIMIDE HAVING POLYAMINE CHAIN LINKED HYDROXYACYL RADICALS AND MINERAL OIL COMPOSITIONS CONTAINING SAME | TEXACO DEVELOPMENT CORPORATION (US) | 1986-10-29 | — | — | EP | disclosed |
| WO-1986001410-A1 | ANTIBODY-METAL ION COMPLEXES | CYTOGEN CORPORATION (US) | 1986-03-13 | — | — | WO | disclosed |
| EP-0173629-A1 | Antibody-metal ion complexes | CYTOGEN CORPORATION (US) | 1986-03-05 | — | — | EP | disclosed |