Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | IGF2R | P11717 | 1/20 | 0.33 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 5/20 | 0.31 |
| ▸ | GJB2 | P29033 | 1/20 | 0.31 |
| ▸ | SELL | P14151 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42792 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 | |
| SCHEMBL16241536 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 | |
| SCHEMBL16241534 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 | |
| SCHEMBL17184967 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 | |
| SCHEMBL42791 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 | |
| SCHEMBL2728425 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 | |
| SCHEMBL30987364 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 | |
| SCHEMBL20533512 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 | |
| SCHEMBL22163862 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 | |
| SCHEMBL33302 | 0.84 | MAPK1 (0.64) | MAPK1NOD2ALDH1A1THRBLGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284767-A | Pyrazines or quinoxalines as the sole carbon, nitrogen and energy source | LONZA LTD. (CH) | 1994-02-08 | — | — | US | disclosed |
| US-5229278-A | Hydroxylating a pyrazine or quinoxaline with a microorganism Rhodococcus or Arthrobacter | LONZA LTD. (CH) | 1993-07-20 | — | — | US | disclosed |