Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.84 |
| ▸ | HPGD | P15428 | 10/20 | 0.84 |
| ▸ | GAA | P10253 | 8/20 | 0.66 |
| ▸ | CASP1 | P29466 | 7/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.66 |
| ▸ | CASP7 | P55210 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107565 | 0.92 | KDM4E (1.00) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL4348338 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL9444346 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL9444270 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL31260252 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL11106592 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL11125976 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL4351260 | 0.77 | KDM4E (0.76) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL9444246 | 0.77 | KDM4E (0.74) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL11488021 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1HPGDGAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5268386-A | Containing a carboxy group | SHIONOGI & CO., LTD. (JP) | 1993-12-07 | — | — | US | disclosed |