SCHEMBL9445329

SCHEMBL9445329

CN(C)C(=O)[N]S(C)(=O)=O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALDH1A1 P00352 2/20 0.48
NFKB1 P19838 1/20 0.48
THPO P40225 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MAPT P10636 1/20 0.48
APEX1 P27695 1/20 0.48
PMP22 Q01453 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL424979 0.67
SCHEMBL6980698 0.67
SCHEMBL5865821 0.67
Diamide SCHEMBL39340 0.65 TSHR (1.00) TSHRALDH1A1NFKB1THPOHSD17B10
Diamide SCHEMBL13680778 0.65 TSHR (1.00) TSHRALDH1A1NFKB1THPOHSD17B10
Diamide SCHEMBL103289 0.65 TSHR (1.00) TSHRALDH1A1NFKB1THPOHSD17B10
SCHEMBL674965 0.65
Diamide SCHEMBL2036888 0.63 TSHR (0.93) TSHRALDH1A1NFKB1THPOHSD17B10
SCHEMBL20348681 0.63
SCHEMBL43201 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5196546-A Aphidicides EASTMAN KODAK COMPANY (US) 1993-03-23 US disclosed
EP-0442564-A1 Selective pyrazoline insecticides and fungicides EASTMAN KODAK COMPANY (US) 1991-08-21 EP disclosed
US-4999368-A Aphidicides EASTMAN KODAK COMPANY (US) 1991-03-12 US disclosed