Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.44 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.44 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.44 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.44 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.44 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446274 | 1.00 | HPGD (0.48) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL9446341 | 1.00 | HPGD (0.48) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL9446349 | 1.00 | HPGD (0.48) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL9446346 | 1.00 | HPGD (0.48) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL9446381 | 1.00 | HPGD (0.48) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL9446287 | 1.00 | HPGD (0.48) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL9446323 | 1.00 | HPGD (0.48) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL9446354 | 0.91 | PSMB11 (0.58) | HPGDALDH1A1HSD17B10PSMB11PSMA7 | |
| SCHEMBL9446317 | 0.88 | PSMB11 (0.57) | HPGDALDH1A1KDM4EPSMB11PSMA7 | |
| SCHEMBL9446348 | 0.83 | TRPV1 (0.47) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |