Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925439 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL746062 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL11795957 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL128273 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL11124054 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL1406142 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL11403346 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL9446574 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL6059940 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL26669506 | 1.00 | HRH1 (0.46) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250603-A | Polyarylene sulfides and bilobal inorganic fiber; improved flexural, tensile and impact strengths; dielectrics | PHILLIPS PETROLEUM COMPANY (US) | 1993-10-05 | — | — | US | disclosed |
| US-5179145-A | Containing an epoxysilane and organic phosphite; molding materials; improved mechanical properties | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-12 | — | — | US | disclosed |
| US-4992497-A | Glass filled poly(arylene sulfide) compositions and methods | PHILLIPS PETROLEUM COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0392472-A2 | Glass-filled poly (arylene sulfide) compositions and methods | PHILLIPS PETROLEUM COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |
| US-3972854-A | ANTIOXIDANT | PHILLIPS PETROLEUM COMPANY (US) | 1976-08-03 | — | — | US | disclosed |