Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26030510 | 0.98 | MAPK1 (0.57) | MAPK1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL20503310 | 0.89 | MAPK1 (0.54) | MAPK1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL845815 | 0.88 | MAPK1 (0.53) | MAPK1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL15878323 | 0.85 | MAPK1 (0.57) | MAPK1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL22120004 | 0.85 | MAPK1 (0.57) | MAPK1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL1441132 | 0.85 | MAPK1 (0.61) | MAPK1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL6205940 | 0.84 | MAPK1 (0.56) | MAPK1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL7419600 | 0.84 | MAPK1 (0.56) | MAPK1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL18929820 | 0.82 | PLK1 (0.57) | KDM4ECA12CA1CA9SMN1; SMN2 | |
| SCHEMBL13606280 | 0.82 | MAPK1 (0.47) | MAPK1L3MBTL1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216170-A | Promoters of livestock; treatment of obesity | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |