Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447160 | 1.00 | OPRL1 (0.40) | OPRL1CYP2C9ARALDH1A1LMNA | |
| SCHEMBL9447045 | 0.99 | OPRL1 (0.40) | OPRL1CYP2C9ARALDH1A1LMNA | |
| SCHEMBL9447049 | 0.99 | OPRL1 (0.40) | OPRL1CYP2C9ARALDH1A1LMNA | |
| SCHEMBL9447038 | 0.99 | OPRL1 (0.40) | OPRL1CYP2C9ARALDH1A1LMNA | |
| SCHEMBL9447128 | 0.96 | OPRL1 (0.38) | OPRL1CYP2C9ARALDH1A1LMNA | |
| SCHEMBL9447123 | 0.96 | OPRL1 (0.38) | OPRL1CYP2C9ARALDH1A1LMNA | |
| SCHEMBL9447349 | 0.92 | OPRL1 (0.39) | OPRL1CYP2C9ARMAPTMEN1 | |
| SCHEMBL9447355 | 0.92 | OPRL1 (0.39) | OPRL1CYP2C9ARMAPTMEN1 | |
| SCHEMBL9447048 | 0.91 | OPRL1 (0.36) | OPRL1CYP2C9ARALDH1A1LMNA | |
| SCHEMBL9447033 | 0.91 | OPRL1 (0.36) | OPRL1CYP2C9ARALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5211878-A | Difluorobenzonitrile derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-05-18 | — | — | US | disclosed |