⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27587419 | 0.81 | — | — | |
| SCHEMBL27587388 | 0.81 | — | — | |
| SCHEMBL27515225 | 0.81 | — | — | |
| SCHEMBL27742785 | 0.79 | — | — | |
| SCHEMBL27807158 | 0.79 | GABRR1 (0.41) | — | |
| SCHEMBL27613857 | 0.79 | — | — | |
| SCHEMBL27667955 | 0.79 | — | — | |
| SCHEMBL27577871 | 0.77 | CYP2D6 (0.36) | — | |
| SCHEMBL27619875 | 0.77 | CYP2D6 (0.36) | — | |
| SCHEMBL27649250 | 0.77 | CYP2D6 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381997-A1 | Microbially prepared N-acetyl-2,3-didehydroleucine acylase, process for its preparation and its use | Degussa Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | claimed |
| WO-2019038655-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-02-28 | — | — | WO | disclosed |
| US-5212069-A | Forming dipeptides from amides and glycine, cysteine or methionine | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1993-05-18 | — | — | US | disclosed |
| US-5134073-A | Culture product of zoogloea ramigera | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1992-07-28 | — | — | US | disclosed |
| EP-0381997-A1 | Microbially prepared N-acetyl-2,3-didehydroleucine acylase, process for its preparation and its use | Degussa Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |
| EP-0381997-A1 | Microbially prepared N-acetyl-2,3-didehydroleucine acylase, process for its preparation and its use | Degussa Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |