Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.68 |
| ▸ | HTR2C | P28335 | 10/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293061 | 0.89 | HTR2A (0.67) | HTR2AHTR2CKMT2AMAPKAPK2 | |
| SCHEMBL945861 | 0.89 | KMT2A (0.62) | HTR2AHTR2CKMT2AMAPKAPK2S1PR1 | |
| Hydrochloric Acid SCHEMBL949135 | 0.88 | KMT2A (0.64) | HTR2AHTR2CKMT2AMAPKAPK2S1PR1 | |
| SCHEMBL32666143 | 0.82 | S1PR1 (0.56) | HTR2AHTR2CKMT2AMAPKAPK2S1PR1 | |
| SCHEMBL8320020 | 0.81 | HTR2A (1.00) | HTR2AHTR2CMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL31293358 | 0.81 | HTR2A (0.67) | HTR2AHTR2CKMT2AMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL31293157 | 0.81 | HTR2A (0.67) | HTR2AHTR2CKMT2AMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL945954 | 0.80 | S1PR1 (0.81) | HTR2AHTR2CKMT2AMAPKAPK2S1PR1 | |
| SCHEMBL11314589 | 0.80 | KMT2A (0.77) | HTR2AHTR2CKMT2AS1PR1 | |
| Hydrochloric Acid SCHEMBL949245 | 0.79 | S1PR1 (0.81) | KMT2AMAPKAPK2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005295-A1 | MODULATORS OF THE SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |