⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichloroethane SCHEMBL916016 | 0.80 | — | — | |
| 1,2-Dichloroethane SCHEMBL22190393 | 0.75 | — | — | |
| Methylene Chloride SCHEMBL669175 | 0.72 | — | — | |
| Methylene Chloride SCHEMBL181202 | 0.72 | — | — | |
| 2-Chloroethanol SCHEMBL11934573 | 0.67 | — | — | |
| 2-Chloroethanol SCHEMBL13916851 | 0.67 | — | — | |
| SCHEMBL11416706 | 0.67 | — | — | |
| 2-Chloroethanol SCHEMBL13916039 | 0.67 | — | — | |
| SCHEMBL18113723 | 0.67 | — | — | |
| 1,2-Dichloroethane SCHEMBL4584447 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751087-A1 | DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F]FLUOROMETHYL)TYROSINE | Piramal Imaging SA (CH) | 2014-07-09 | — | — | EP | disclosed |
| US-8513366-B2 | Methods for modulated degenerative transfer living polymerization and isotactic-atactic stereoblock and stereogradient poly(olefins) thereby | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2013-08-20 | — | — | US | disclosed |
| WO-2013001088-A1 | DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F]FLUOROMETHYL) TYROSINE | PIRAMAL IMAGING SA (CH) | 2013-01-03 | — | — | WO | disclosed |
| US-7868088-B2 | Methods for modulated degenerative transfer living polymerization and isotactic-atactic stereoblock and stereogradient poly(olefins) thereby | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2011-01-11 | — | — | US | disclosed |
| US-20090220786-A1 | Methods for Modulated Degenerative Transfer Living Polymerization and Isotactic-Atactic Stereoblock and Stereogradient Poly(Olefins) Thereby | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2009-09-03 | — | — | US | disclosed |
| US-20090209703-A1 | Methods for Modulated Degenerative Transfer Living Polymerization and Isotactic-Atactic Stereoblock and Stereogradient Poly(Olefins) Thereby | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2009-08-20 | — | — | US | disclosed |