Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 6/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448012 | 1.00 | SRD5A1 (0.40) | SRD5A1STSTACR1PTPN2PTPN1 | |
| Hydrochloric Acid SCHEMBL9448431 | 0.99 | SRD5A1 (0.40) | SRD5A1STSTACR1PTPN2PTPN1 | |
| Hydrochloric Acid SCHEMBL9448433 | 0.99 | SRD5A1 (0.40) | SRD5A1STSTACR1PTPN2PTPN1 | |
| SCHEMBL9448176 | 0.89 | SRD5A1 (0.41) | SRD5A1STSHTR2CHTR2B | |
| SCHEMBL9448180 | 0.89 | SRD5A1 (0.41) | SRD5A1STSHTR2CHTR2B | |
| SCHEMBL9448258 | 0.88 | SRD5A1 (0.39) | SRD5A1STSUBE2MDCUN1D1HTR2A | |
| SCHEMBL9448251 | 0.88 | SRD5A1 (0.39) | SRD5A1STSUBE2MDCUN1D1HTR2A | |
| Hydrochloric Acid SCHEMBL9448117 | 0.88 | SRD5A1 (0.40) | SRD5A1STSHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL9448434 | 0.88 | SRD5A1 (0.38) | SRD5A1STSUBE2MDCUN1D1HTR2A | |
| Hydrochloric Acid SCHEMBL9448438 | 0.88 | SRD5A1 (0.38) | SRD5A1STSUBE2MDCUN1D1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0461353-A1 | Biogenic amine uptake inhibitors | ABBOTT LABORATORIES (US) | 1991-12-18 | — | — | EP | disclosed |