Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855233 | 0.82 | MAPT (0.57) | ELANENPSR1MAPTALDH1A1HPGD | |
| SCHEMBL5272364 | 0.81 | ELANE (0.58) | ELANENPSR1MAPTKDM4EALDH1A1 | |
| SCHEMBL19294157 | 0.81 | ELANE (0.49) | ELANENPSR1MAPTKDM4EALDH1A1 | |
| SCHEMBL12164540 | 0.81 | ELANE (0.49) | ELANENPSR1MAPTKDM4EALDH1A1 | |
| SCHEMBL19133153 | 0.81 | ELANE (0.49) | ELANENPSR1MAPTKDM4EALDH1A1 | |
| SCHEMBL14665938 | 0.79 | HSD17B10 (0.65) | ELANENPSR1MAPTKDM4EALDH1A1 | |
| SCHEMBL15445468 | 0.79 | ELANE (0.47) | ELANEMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL17863863 | 0.78 | KCNK3 (0.50) | ELANEALDH1A1L3MBTL1 | |
| SCHEMBL18195534 | 0.78 | CTNNB1 (0.61) | ELANENPSR1MAPTALDH1A1HSD17B10 | |
| SCHEMBL17863859 | 0.78 | IRAK4 (0.64) | ELANENPSR1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544812-A1 | BISPHOSPHONIC ACID DERIVATIVES AS ANTI-ARTHRITIC AGENTS. | UPJOHN CO (US) | 1993-06-09 | — | — | EP | disclosed |