Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450601 | 1.00 | KMT2A (0.55) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL9450597 | 1.00 | KMT2A (0.55) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL14973545 | 0.94 | KMT2A (0.60) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL9450633 | 0.91 | HTT (0.58) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL14994325 | 0.89 | KMT2A (0.51) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL3657694 | 0.89 | HTT (0.59) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL3658650 | 0.87 | HTT (0.62) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL576794 | 0.85 | KMT2A (0.56) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL3657063 | 0.82 | HTT (0.56) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL20968646 | 0.81 | POLB (0.51) | KMT2AMEN1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559789-A1 | PROCESS FOR THE PREPARATION OF $g(a)-ALKYL LACTONES | HENKEL CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5231192-A | Reacting an a-acyl lactone, an aldehyde and an alkali metal hydroxide; hydrogenation | HENKEL CORPORATION (US) | 1993-07-27 | — | — | US | disclosed |
| WO-1992009590-A1 | PROCESS FOR THE PREPARATION OF α-ALKYL LACTONES | HENKEL CORPORATION (US) | 1992-06-11 | — | — | WO | disclosed |
| US-4980342-A | Process for the preparation of α-alkyl lactones | HENKEL CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |