SCHEMBL9450686

SCHEMBL9450686

NC(=O)c1c(Cl)ccc(Cl)c1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.58
ALDH1A1 P00352 5/20 0.50
KDM4E B2RXH2 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TSHR P16473 4/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
CXCR2 P25025 2/20 0.41
TP53 P04637 1/20 0.40
MAPT P10636 3/20 0.38
POLB P06746 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CXCR1 P25024 1/20 0.38
PBRM1 Q86U86 1/20 0.38
CYP3A4 P08684 1/20 0.37
PARP1 P09874 1/20 0.37
CYP2C19 P33261 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486824 0.87 DPP4 (0.71) DPP4ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL11238802 0.87 DPP4 (0.50) DPP4ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL11238797 0.87 DPP4 (0.50) DPP4ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL16702731 0.85 DPP4 (0.68) DPP4ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL28737172 0.85 DPP4 (0.68) DPP4ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL21750029 0.79 DPP4 (0.56) DPP4ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL8587726 0.76 DPP4 (0.64) DPP4ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL10771891 0.76 DPP4 (0.58) DPP4ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL218985 0.76 DPP4 (0.58) DPP4ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL9681770 0.76 DPP4 (0.58) DPP4ALDH1A1KDM4EHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 EP disclosed
US-5187143-A Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-02-16 US disclosed
EP-0482668-A1 Heat sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-04-29 EP disclosed
EP-0465323-A1 Pyrimidin derivatives, angiotensin II receptor antagonists, their process of preparation and pharmaceutical compositions containing them LABORATOIRES UPSA (FR) 1992-01-08 EP disclosed
EP-0013900-B1 PROCESS FOR THE CONTINUOUS PRODUCTION OF ISATOIC ANHYDRIDE BASF Aktiengesellschaft (DE) 1982-12-01 EP disclosed
US-4328339-A Continuous preparation of isatoic anhydride BASF AKTIENGESELLSCHAFT (DE) 1982-05-04 US disclosed
EP-0013900-A1 Process for the continuous production of isatoic anhydride BASF Aktiengesellschaft (DE) 1980-08-06 EP disclosed
US-3984406-A FROM AN ALKALI METAL PHTHALAMATE AND A HYPOHALITE IN A HALOGEN CATALYST BASF AKTIENGESELLSCHAFT (DT) 1976-10-05 US disclosed