Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 18/20 | 0.46 |
| ▸ | CCR3 | P51677 | 18/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997602 | 0.88 | HRH1 (0.53) | SLC6A2SLC6A4SLC6A3HRH1CCR3 | |
| SCHEMBL9596483 | 0.86 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HRH1CCR3 | |
| SCHEMBL10608408 | 0.86 | HRH1 (0.46) | SLC6A2SLC6A4SLC6A3HRH1CCR3 | |
| SCHEMBL10606839 | 0.85 | HRH1 (0.58) | SLC6A2SLC6A4SLC6A3HRH1CCR3 | |
| SCHEMBL9450769 | 0.82 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3HRH1CCR3 | |
| SCHEMBL9450741 | 0.82 | EPHX2 (0.49) | SLC6A2SLC6A4SLC6A3HRH1CCR3 | |
| SCHEMBL5469410 | 0.80 | USP30 (0.47) | SLC6A2SLC6A4SLC6A3HRH1CCR3 | |
| SCHEMBL9450767 | 0.80 | EPHX2 (0.53) | SLC6A2SLC6A4SLC6A3HRH1CCR3 | |
| SCHEMBL9805858 | 0.79 | KDM4E (0.48) | SLC6A2SLC6A4SLC6A3HRH1CCR3 | |
| SCHEMBL10971223 | 0.79 | HRH1 (0.52) | SLC6A2SLC6A4SLC6A3HRH1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560905-A1 | 3-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-1-AZETIDINE CARBOXAMIDES HAVING ANTICONVULSANT ACTIVITY. | ROBINS CO INC A H (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5183902-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-02-02 | — | — | US | disclosed |
| US-5151418-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-09-29 | — | — | US | disclosed |
| WO-1992010474-A1 | 3-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-1-AZETIDINE CARBOXAMIDES HAVING ANTICONVULSANT ACTIVITY | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-06-25 | — | — | WO | disclosed |
| US-5095014-A | 3-(2-chloro-4-(trifluoromethyl)phenoxy)-1-azetidine carboxamides having anticonvulsant activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-03-10 | — | — | US | disclosed |
| US-5068231-A | Ureas and thioureas for relaxing muscles | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| US-4956359-A | CARBOXAMIDES OR THIOCARBOXAMIDES OF ARYL OXY OR THIO AZETIDINES | A. H. ROBINS COMPANY, INC. (US) | 1990-09-11 | — | — | US | disclosed |