Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.58 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.58 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.53 |
| ▸ | GRM6 | O15303 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099715 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 | |
| SCHEMBL29710629 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 | |
| SCHEMBL30099611 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 | |
| SCHEMBL14490692 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 | |
| SCHEMBL11886061 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 | |
| SCHEMBL1674796 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 | |
| SCHEMBL20739235 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 | |
| SCHEMBL22111146 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 | |
| SCHEMBL20739236 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 | |
| SCHEMBL30099588 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLADPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250123280-A1 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | UNIV OREGON HEALTH & SCIENCE (US) | 2025-04-17 | — | — | US | claimed |
| WO-2023003984-A2 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-01-26 | — | — | WO | claimed |
| CN-122070294-A | Stable vitreous material based on histidine, arginine and glutamic acid amino acids | 阵序补丁有限公司 | 2026-05-19 | — | — | CN | disclosed |
| US-20250123280-A1 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | UNIV OREGON HEALTH & SCIENCE (US) | 2025-04-17 | — | — | US | disclosed |
| WO-2025032025-A1 | STABLE GLASSY MATERIAL BASED ON HISTIDINE, ARGININE AND GLUTAMIC ACID AMINO ACIDS | VITROPEP (FR) | 2025-02-13 | — | — | WO | disclosed |
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | Sumitomo Pharma Co., Ltd. (JP) | 2024-06-25 | — | — | US | disclosed |
| WO-2023003984-A2 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-01-26 | — | — | WO | disclosed |
| US-20200247845-A1 | Hemiasterlin Derivatives and Antibody-Drug Conjugates Including Same | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-06 | — | — | US | disclosed |
| EP-3666788-A1 | HEMIASTERLIN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES INCLUDING SAME | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |
| WO-2019031615-A1 | HEMIASTERLIN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES INCLUDING SAME | 大日本住友製薬株式会社 | 2019-02-14 | — | — | WO | disclosed |
| EP-0535162-A1 | ANALYTE VARIANT ANALYSIS. | AXIS RESEARCH (NO) | 1993-04-07 | — | — | EP | disclosed |
| WO-1991019983-A1 | ANALYTE VARIANT ANALYSIS | AXIS RESEARCH AS (NO) | 1991-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247845-A1 | Hemiasterlin Derivatives and Antibody-Drug Conjugates Including Same | FCGRT, QARS1, INHA | FOLH1 4072/4885NAALAD2 984/4885RIMKLA 1754/4885 |
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | FCGRT, QARS1, INHA | FOLH1 4072/4885NAALAD2 984/4885RIMKLA 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.