Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 10/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TPH1 | P17752 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428468 | 0.89 | S1PR1 (0.54) | S1PR1 | |
| SCHEMBL3426943 | 0.86 | S1PR1 (0.43) | S1PR1HDAC1HDAC8HDAC6 | |
| SCHEMBL946557 | 0.86 | S1PR1 (0.48) | S1PR1HDAC1HDAC8HDAC6 | |
| SCHEMBL3750093 | 0.85 | MAPT (0.43) | MAPTTP53POLBSMN1; SMN2LMNA | |
| SCHEMBL3752423 | 0.85 | S1PR1 (0.55) | S1PR1 | |
| SCHEMBL3428752 | 0.84 | S1PR1 (0.47) | S1PR1HDAC1HDAC8HDAC6PLAT | |
| SCHEMBL3429275 | 0.83 | S1PR1 (0.43) | S1PR1 | |
| SCHEMBL3430744 | 0.83 | S1PR1 (0.55) | S1PR1 | |
| SCHEMBL946044 | 0.83 | S1PR1 (0.42) | S1PR1HDAC1HDAC8HDAC6 | |
| SCHEMBL3429709 | 0.83 | S1PR1 (0.54) | S1PR1HDAC1HDAC8HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005290-A1 | DISUBSTITUTED OXADIAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |