Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350015 | 0.90 | CYP11B1 (0.41) | CYP11B1CYP11B2GRM2ALDH1A1 | |
| SCHEMBL10502378 | 0.89 | CYP11B1 (0.40) | CYP11B1CYP11B2GRM2ALDH1A1 | |
| SCHEMBL10501859 | 0.89 | CYP11B1 (0.40) | CYP11B1CYP11B2GRM2ALDH1A1 | |
| SCHEMBL10501185 | 0.89 | CYP11B1 (0.40) | CYP11B1CYP11B2GRM2ALDH1A1 | |
| SCHEMBL10768678 | 0.88 | CYP11B1 (0.40) | CYP11B1CYP11B2GRM2ALDH1A1 | |
| SCHEMBL10349795 | 0.86 | CYP11B1 (0.42) | CYP11B1CYP11B2PGR | |
| SCHEMBL9556246 | 0.86 | CYP11B1 (0.39) | CYP11B1CYP11B2GRM2PGR | |
| SCHEMBL9556251 | 0.86 | CYP11B1 (0.39) | CYP11B1CYP11B2GRM2PGR | |
| SCHEMBL10501930 | 0.85 | GRM2 (0.35) | GRM2ALDH1A1 | |
| SCHEMBL9556284 | 0.85 | CYP11B1 (0.38) | CYP11B1CYP11B2GRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190689-A | Polymer materials having liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0220463-B1 | POLYMER MATERIALS PRESENTING A LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0220463-A2 | Polymer materials presenting a liquid crystal phase | MERCK PATENT GmbH (DE) | 1987-05-06 | — | — | EP | disclosed |