Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27692545 | 0.79 | TSHR (1.00) | TSHRMAOAMAOBCYP2A6SIGMAR1 | |
| SCHEMBL11606739 | 0.79 | TSHR (1.00) | TSHRMAOAMAOBCYP2A6SIGMAR1 | |
| SCHEMBL29358070 | 0.79 | TSHR (1.00) | TSHRMAOAMAOBCYP2A6SIGMAR1 | |
| SCHEMBL11645158 | 0.79 | TSHR (1.00) | TSHRMAOAMAOBCYP2A6SIGMAR1 | |
| SCHEMBL385555 | 0.79 | TSHR (1.00) | TSHRMAOAMAOBCYP2A6SIGMAR1 | |
| SCHEMBL8355 | 0.79 | TSHR (1.00) | TSHRMAOAMAOBCYP2A6SIGMAR1 | |
| SCHEMBL25404307 | 0.76 | TSHR (0.93) | TSHRMAOAMAOBCYP2A6SIGMAR1 | |
| SCHEMBL10691938 | 0.76 | TSHR (0.93) | TSHRMAOAMAOBCYP2A6SIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL1240223 | 0.76 | TSHR (0.93) | TSHRMAOAMAOBCYP2A6SIGMAR1 | |
| SCHEMBL8721156 | 0.76 | TSHR (0.93) | TSHRMAOAMAOBCYP2A6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254739-A | Heating a-acetylbutyrolactone in presence of a halide | CIBA-GEIGY CORPORATION (US) | 1993-10-19 | — | — | US | disclosed |