Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | AKT1 | P31749 | 3/20 | 0.60 |
| ▸ | CDC25A | P30304 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL7156030 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 | |
| SCHEMBL11675849 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 | |
| SCHEMBL9584746 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 | |
| SCHEMBL3965401 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 | |
| SCHEMBL16371727 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 | |
| SCHEMBL23112858 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 | |
| SCHEMBL3240611 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 | |
| SCHEMBL4639710 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 | |
| SCHEMBL11675710 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 | |
| SCHEMBL3967255 | 0.95 | CYP3A4 (0.61) | CYP3A4AKT1CDC25ALMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302545-A1 | Method of Using PI3K and MEK Modulators | EXELIXIS, INC. (US) | 2012-11-29 | — | — | US | claimed |
| CN-112055743-B | Lubricant with high pyrophosphate content | 路博润公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-108473902-B | High pyrophosphate level lubricants | 路博润公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113265277-A | Clean synthetic fuel for ignition type engine | 国供能源(福建)有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-112055743-A | Lubricant with high pyrophosphate content | 路博润公司 | 2020-12-08 | — | — | CN | disclosed |
| WO-2020226106-A1 | LUBRICATION METHOD | ＪＸＴＧエネルギー株式会社 | 2020-11-12 | — | — | WO | disclosed |
| CN-110964578-B | Methanol fuel for vehicle | 大容新能源科技(深圳)有限公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-110964578-A | Methanol fuel for vehicle | 大容新能源科技(深圳)有限公司 | 2020-04-07 | — | — | CN | disclosed |
| EP-1712606-B1 | LUBRICATING OIL COMPOSITION | JX NIPPON OIL & ENERGY CORP (JP) | 2016-07-06 | — | — | EP | disclosed |
| US-9157046-B2 | Lubricating oil composition | NIPPON OIL CORPORATION (JP) | 2015-10-13 | — | — | US | disclosed |
| US-20060111256-A1 | Having a diurea thickener with at least one aromatic or aliphatic ring, paraffin oxides phosphite or phosphate compounds, a organic molybdenum compound and a lithium soap added to the base oil; improved friction resistance at high temperatures | NIPPPON OIL CORPORATION (JP) | 2006-05-25 | — | — | US | disclosed |
| EP-1559771-A1 | GREASE COMPOSITION | Nippon Oil Corporation (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-20050130855-A1 | Lubricating oil compositions | NIPPON OIL CORPORATION | 2005-06-16 | — | — | US | disclosed |
| US-20050130854-A1 | Comprises calcium salicylate and phosphorus compounds; improved anti-wear properties and long drain properties; for internal combustion engines | NIPPON OIL CORPORATION | 2005-06-16 | — | — | US | disclosed |
| US-20050113265-A1 | Lubricating oil additives, lubricating oil compositions containing such additives and processes for producing such additives and compositions | NIPPON OIL CORPORATION | 2005-05-26 | — | — | US | disclosed |
| US-20050107269-A1 | Lubricating oil compositions | NIPPON OIL CORPORATION | 2005-05-19 | — | — | US | disclosed |
| EP-1516911-A1 | LUBRICATING OIL ADDITIVE, LUBRICATING OIL COMPOSITION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME | Nippon Oil Corporation (JP) | 2005-03-23 | — | — | EP | disclosed |
| US-6656887-B2 | Metal salt or amine salt of thiophosphate or of phosphate are decreased in sulfur content and excellent in the ability to maintain the total base number | NIPPON MITSUBISHI OIL CORPORATION (JP) | 2003-12-02 | — | — | US | disclosed |
| US-20020142922-A1 | Lubricating oil compositions | NIPPON MITSUBISHI OIL CORPORATION | 2002-10-03 | — | — | US | disclosed |
| EP-1227145-A1 | Lubricating oil compositions | Nippon Mitsubishi Oil Corporation (JP) | 2002-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302545-A1 | Method of Using PI3K and MEK Modulators | PIK3CA, PIK3CD, PIK3R1 | CYP3A4 1201/4885AKT1 29/4885CDC25A 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.