SCHEMBL9456743

SCHEMBL9456743

c1ccc2c(CSCc3cccc4ccccc34)cccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 1.00
CYP2C19 P33261 4/20 1.00
CYP2C9 P11712 2/20 1.00
HTT P42858 2/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
CYP2D6 P10635 3/20 0.59
HPGD P15428 2/20 0.59
ALDH1A1 P00352 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
TDP1 Q9NUW8 1/20 0.50
MCL1 Q07820 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
ACP3 P15309 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7520769 0.87 CYP1A2 (0.77) CYP1A2CYP2C19CYP2C9HTTMEN1
SCHEMBL9867788 0.84 CYP1A2 (0.71) CYP1A2CYP2C19CYP2C9HTTMEN1
SCHEMBL8586266 0.84 CYP1A2 (0.70) CYP1A2CYP2C19CYP2C9HTTMEN1
SCHEMBL29281804 0.83 CYP1A2 (0.70) CYP1A2CYP2C19CYP2C9HTTMEN1
SCHEMBL9280807 0.82 CYP1A2 (0.69) CYP1A2CYP2C19CYP2C9HTTMEN1
SCHEMBL271106 0.82 CYP1A2 (0.69) CYP1A2CYP2C19CYP2C9HTTMEN1
SCHEMBL271107 0.82 CYP1A2 (0.69) CYP1A2CYP2C19CYP2C9HTTMEN1
SCHEMBL8813943 0.82 CYP1A2 (0.69) CYP1A2CYP2C19CYP2C9HTTMEN1
SCHEMBL5638078 0.81 CYP1A2 (1.00) CYP1A2CYP2C19CYP2C9HTTMEN1
SCHEMBL27281987 0.80 CYP1A2 (0.67) CYP1A2CYP2C19CYP2C9HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
CN-111517902-A Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2020-08-11 CN disclosed
US-5247113-A Curing agents or curing accelerators for epoxy resins CIBA-GEIGY CORPORATION (US) 1993-09-21 US disclosed
EP-0379464-B1 ARALIPHATIC SULFONIUM SALTS AND THEIR USE CIBA-GEIGY AG (CH) 1993-02-10 EP disclosed
US-5013814-A Araliphatic sulfonium salts and their use CIBA-GEIGY CORPORATION (US) 1991-05-07 US disclosed
EP-0379464-A1 Araliphatic sulfonium salts and their use CIBA-GEIGY AG (CH) 1990-07-25 EP disclosed
US-4783562-A Process for the preparation of trichloromethyl-substituted aromatic compounds, and trichloromethyl-substituted aromatic compounds obtained in this process BAYER AKTIENGESELLSCHAFT (DE) 1988-11-08 US disclosed
US-4505860-A Cyclic keto-butyraldehydes a process for their preparation, and their use in the preparation of cyclic diisocyanates BAYER AKTIENGESELLSCHAFT (DE) 1985-03-19 US disclosed
EP-0100479-B1 3-(AMINOMETHYL)-1-(3-AMINOPROPYL-1-METHYL)-4-METHYL CYCLOHEXANE, PROCESS FOR ITS PREPARATION AND ITS USE BAYER AG (DE) 1985-03-13 EP disclosed
US-4487966-A 3-Aminomethyl-1-(3-aminopropyl-1-methyl)-4-methylcyclohexane, a process for its preparation and its use BAYER AKTIENGESELLSCHAFT (DE) 1984-12-11 US disclosed
EP-0008763-B1 AMINOMETHYL-CYCLODODECANES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTICORROSIVES BAYER AG (DE) 1981-04-01 EP disclosed
US-4251462-A REACTING 1,5,9-CYCLODODECATRIENE WITH CARBON MONOXIDE AND HYDROGEN, REMOVING CATALYST, REACTING WITH HYDROGEN AND AMMONIA BAYER AKTIENGESELLSCHAFT (DE) 1981-02-17 US disclosed
EP-0008763-A1 Aminomethyl-cyclododecanes, a process for their preparation and their use as anticorrosives BAYER AG (DE) 1980-03-19 EP disclosed