Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187751 | 1.00 | HRH3 (0.47) | HRH3CA1CA2HRH4TAAR1 | |
| Water SCHEMBL11480029 | 0.97 | HRH3 (0.45) | HRH3CA1CA2HRH4TAAR1 | |
| SCHEMBL22156858 | 0.91 | HRH3 (0.41) | HRH3CA1CA2HRH4TAAR1 | |
| SCHEMBL97582 | 0.89 | CA1 (0.52) | HRH3CA1CA2TAAR1TSHR | |
| SCHEMBL1071609 | 0.88 | TAAR1 (0.56) | TAAR1ABCC4LMNAGAATSHR | |
| SCHEMBL2069301 | 0.88 | MAOB (0.54) | CA1CA2TAAR1MAOBLMNA | |
| SCHEMBL3599879 | 0.86 | NPC1 (0.48) | HRH3CA2TAAR1GAATSHR | |
| SCHEMBL16253356 | 0.86 | HRH3 (0.74) | HRH3TAAR1MAOB | |
| SCHEMBL1725688 | 0.86 | MAOB (0.52) | CA1CA2TAAR1MAOBIDO1 | |
| SCHEMBL9023183 | 0.86 | IDO1 (0.46) | HRH3TAAR1LMNAIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229481-A | High-molecular weight, silicon-containing polymers and methods for the preparation and use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-07-20 | — | — | US | disclosed |
| US-4248976-A | COMPRISING A PHOSPHORUS COMPOUND AND AN AROMATIC COMPOUND | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |
| US-4172858-A | Flame-resistant polymer compositions | CIBA-GEIGY AG (CH) | 1979-10-30 | — | — | US | disclosed |
| US-4163731-A | HYDRAULIC FLUIDS | CIBA-GEIGY AG (CH) | 1979-08-07 | — | — | US | disclosed |