SCHEMBL9457340

SCHEMBL9457340

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC(I)CC

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 2/20 0.43
OPRM1 P35372 1/20 0.42
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39
MAPT P10636 1/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1001820 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL18107258 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL10600001 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL1000844 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL18107314 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL14964587 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL20957527 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL21493266 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL20957524 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL18107351 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326586-B1 PHOSPHITE ESTER COMPOSITIONS, AND LUBRICANTS AND FUNCTIONAL FLUIDS CONTAINING SAME The Lubrizol Corporation (US) 1993-03-17 EP disclosed
US-4752416-A MIXTURE WITH SULFUR CONTAINING COMPOUNDS THE LUBRIZOL CORPORATION (US) 1988-06-21 US disclosed
US-4016150-A Sulfur and nitrogen-containing organic compositions processes for making them and fuels and additives containing them THE LUBRIZOL CORPORATION (US) 1977-04-05 US disclosed