SCHEMBL9457396

SCHEMBL9457396

O=C(c1ccccc1)[C@@]1(O)[C@](O)(C(=O)c2ccccc2)[C@@](O)(C(=O)c2ccccc2)[C@H](O)[C@@](O)(C(=O)c2ccccc2)[C@]1(O)C(=O)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.38
CES2 O00748 3/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
MAPK1 P28482 3/20 0.36
TRPA1 O75762 1/20 0.36
GSK3B P49841 1/20 0.36
HIF1A Q16665 1/20 0.36
AKT1 P31749 1/20 0.36
LMNA P02545 2/20 0.36
TDP1 Q9NUW8 3/20 0.35
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.35
CA2 P00918 2/20 0.35
CA4 P22748 2/20 0.35
POLB P06746 1/20 0.35
PARP1 P09874 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9458212 0.88 CES1 (0.44) CES1CES2ALDH1A1TSHRDAO
SCHEMBL9457418 0.85 CES1 (0.35) CES1CES2ALDH1A1TSHRDAO
SCHEMBL9457264 0.81 CES1 (0.38) CES1CES2ALDH1A1TSHRDAO
SCHEMBL9767728 0.78 CES1 (0.42) CES1CES2ALDH1A1TSHRDAO
SCHEMBL9767733 0.78 CES1 (0.42) CES1CES2ALDH1A1TSHRDAO
SCHEMBL9457300 0.75 CES1 (0.44) CES1CES2ALDH1A1TSHRDAO
SCHEMBL9457279 0.74 CES1 (0.35) CES1CES2ALDH1A1TSHRDAO
SCHEMBL9457369 0.74 CES1 (0.35) CES1CES2ALDH1A1TSHRDAO
SCHEMBL9439539 0.74 TDP1 (0.36) ALDH1A1TSHRMAPK1TRPA1GSK3B
SCHEMBL9767838 0.73 CES1 (0.46) CES1CES2ALDH1A1TSHRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5264605-A Myoinsitol derivatives, process for preparing same, phosphorylating agent, and its utilization MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-11-23 US disclosed
EP-0431197-A1 MYOINOSITOL DERIVATIVE AND METHOD OF PRODUCTION THEREOF, AND PHOSPHORYLATING AGENT AND ITS USE MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-06-12 EP disclosed