Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.66 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.66 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.66 |
| ▸ | GSK3B | P49841 | 12/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 1/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457131 | 1.00 | KCNH2 (0.66) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9457137 | 1.00 | KCNH2 (0.66) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL8918812 | 0.93 | KCNH2 (0.68) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9457828 | 0.91 | KCNH2 (0.65) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9457226 | 0.91 | KCNH2 (0.65) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9457229 | 0.91 | KCNH2 (0.65) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9428498 | 0.90 | KCNH2 (0.63) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9428507 | 0.90 | KCNH2 (0.63) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9022902 | 0.88 | KCNH2 (0.65) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL10679942 | 0.88 | KCNH2 (0.65) | KCNH2POLBCACNA1FMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258528-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1993-11-02 | — | — | US | disclosed |