Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Octadecylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD known ✓ | Q03181 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.77 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.63 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.63 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.63 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.61 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.61 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL9404153 | 1.00 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Hexadecylamine SCHEMBL27769741 | 1.00 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Hexadecylamine SCHEMBL27769738 | 1.00 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Octadecylamine SCHEMBL9458208 | 1.00 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Dodecylamine SCHEMBL9441764 | 1.00 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Dodecylamine SCHEMBL9441770 | 1.00 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL28088035 | 0.98 | GSR (0.80) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL26634433 | 0.98 | GSR (0.80) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL30120681 | 0.95 | GSR (0.69) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL30120687 | 0.95 | GSR (0.69) | GSRGNAI3GNAO1GNAI1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266321-A | Oil, silicone gel and powder | KOBAYASHI KOSE CO., LTD. (JP) | 1993-11-30 | — | — | US | disclosed |