Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.70 |
| ▸ | HPGD | P15428 | 7/20 | 0.70 |
| ▸ | GAA | P10253 | 5/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.70 |
| ▸ | RELA | Q04206 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 8/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741369 | 0.89 | MAPT (0.68) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL6741363 | 0.89 | MAPT (0.68) | MAPTKDM4EALDH1A1HPGDGAA | |
| Hydrochloric Acid SCHEMBL5703112 | 0.88 | MAPT (0.67) | MAPTKDM4EALDH1A1HPGDGAA | |
| Hydrochloric Acid SCHEMBL5703118 | 0.88 | MAPT (0.67) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL4322243 | 0.84 | MAPT (0.75) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL4322240 | 0.84 | MAPT (0.75) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL28377843 | 0.82 | MAPT (0.72) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL28215466 | 0.81 | MAPT (0.67) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8343548 | 0.80 | MAPT (0.69) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8343557 | 0.80 | MAPT (0.69) | MAPTKDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204311-A | Yellow colored coordination compounds of transition metals | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0531020-A1 | Ethanediimidic acid bis arylalkylidene)hydrazide | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |