Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458397 | 1.00 | HRH3 (0.39) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL9326742 | 0.96 | GRIA1 (0.41) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL9326749 | 0.96 | GRIA1 (0.41) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL9328535 | 0.92 | GRIA1 (0.40) | GRIA1GRIA2GRIA3EGLN2USP30 | |
| SCHEMBL9328548 | 0.92 | GRIA1 (0.40) | GRIA1GRIA2GRIA3EGLN2USP30 | |
| SCHEMBL7691957 | 0.92 | GRIA1 (0.40) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL7691956 | 0.92 | GRIA1 (0.40) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL9502394 | 0.91 | GRIA1 (0.39) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL2277181 | 0.88 | GRIA1 (0.42) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL2277177 | 0.88 | GRIA1 (0.42) | GRIA1GRIA2GRIA3USP30ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238602-A | Electrooptical cells | HOFFMANN LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |