Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763701 | 0.79 | MAPT (0.32) | MAPT | |
| SCHEMBL11957121 | 0.78 | DPP4 (0.34) | DPP4MAPT | |
| SCHEMBL477760 | 0.76 | — | — | |
| SCHEMBL1623070 | 0.70 | — | — | |
| SCHEMBL28520620 | 0.68 | — | — | |
| SCHEMBL17260756 | 0.68 | KMT2A (0.46) | DPP4MAPT | |
| SCHEMBL4418711 | 0.68 | KMT2A (0.46) | DPP4MAPT | |
| SCHEMBL7861291 | 0.67 | MAPT (0.38) | MAPT | |
| SCHEMBL7745759 | 0.67 | — | — | |
| SCHEMBL388063 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194650-A | Chemical intermediates which can be hydrolyzed to form arylcyclohexadionethiocarboxylic S-ester as bioregulators | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| US-5130453-A | Multistage reaction of acylcyclohexadione, reaction with hydroxylamine derivative and mercaptan | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |