Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12543376 | 1.00 | TSHR (0.58) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL20394070 | 1.00 | TSHR (0.58) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL35210216 | 1.00 | TSHR (0.58) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL10585558 | 0.90 | TSHR (0.69) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL1275661 | 0.90 | TSHR (0.69) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9115198 | 0.90 | TSHR (0.69) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL8962376 | 0.90 | TSHR (0.69) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL890675 | 0.90 | TSHR (0.69) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL257295 | 0.89 | CYP3A4 (0.70) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL35210221 | 0.87 | CYP3A4 (0.55) | TSHRCYP3A4ATMTDP1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2392400-B1 | Homogeneous asymmetric hydrogenation method | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2392400-A2 | Homogeneous asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 2011-12-07 | — | — | EP | disclosed |
| US-5206129-A | Coupling reaction with oxidized species of primary aromatic amine derivative; improved color reproduction | FUJI PHOTO FILM CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |