Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | GABRE | P78334 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Allothreonine SCHEMBL222076 | 1.00 | — | — | |
| Threonine SCHEMBL16111860 | 1.00 | SLC7A5 (0.63) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| Threonine SCHEMBL6038228 | 1.00 | SLC7A5 (0.63) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| Threonine SCHEMBL92730 | 1.00 | — | — | |
| Threonine SCHEMBL14946556 | 1.00 | — | — | |
| Threonine SCHEMBL2702066 | 1.00 | SLC7A5 (0.63) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| Threonine SCHEMBL18050157 | 1.00 | SLC7A5 (0.63) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| Threonine SCHEMBL18050155 | 1.00 | SLC7A5 (0.63) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| Threonine SCHEMBL117301 | 1.00 | — | — | |
| Threonine SCHEMBL1480 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3267993-A1 | THERAPEUTIC CYCLIC COMPOUNDS AS IMMUNOMODULATORS | Aurigene Discovery Technologies Limited (IN) | 2018-01-17 | — | — | EP | disclosed |
| WO-2016142835-A1 | THERAPEUTIC CYCLIC COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2016-09-15 | — | — | WO | disclosed |
| US-5264353-A | Culture of Providencia with nutrients | TORAY INDUSTRIES, INC. (JP) | 1993-11-23 | — | — | US | disclosed |