Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461816 | 1.00 | SLC1A2 (0.60) | SLC1A2PPARGPPARAGPR132LMNA | |
| SCHEMBL9461814 | 1.00 | SLC1A2 (0.60) | SLC1A2PPARGPPARAGPR132LMNA | |
| SCHEMBL5580937 | 0.91 | SLC1A2 (0.54) | SLC1A2PPARGPPARAGPR132LMNA | |
| SCHEMBL9829118 | 0.89 | NPC1 (0.56) | SLC1A2PPARGPPARAGPR132LMNA | |
| SCHEMBL9829127 | 0.89 | NPC1 (0.56) | SLC1A2PPARGPPARAGPR132LMNA | |
| SCHEMBL22338822 | 0.85 | GAA (0.51) | SLC1A2PPARGPPARALMNAHPGD | |
| SCHEMBL22303090 | 0.85 | GAA (0.51) | SLC1A2PPARGPPARALMNAHPGD | |
| SCHEMBL22304180 | 0.85 | GAA (0.51) | SLC1A2PPARGPPARALMNAHPGD | |
| SCHEMBL22303089 | 0.85 | GAA (0.51) | SLC1A2PPARGPPARALMNAHPGD | |
| SCHEMBL1168553 | 0.84 | SLC1A2 (0.66) | SLC1A2PPARGPPARALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219731-A | Cleaving an oxazolone precursor with lipase | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1993-06-15 | — | — | US | disclosed |