SCHEMBL9462004

SCHEMBL9462004

CCN(C=O)C(=O)N(C)C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.33
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.31
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21675936 0.78
SCHEMBL8572251 0.74
SCHEMBL6451600 0.74
Hydrochloric Acid SCHEMBL11686526 0.72
SCHEMBL11686522 0.72
SCHEMBL14855811 0.72
SCHEMBL8942761 0.72
SCHEMBL11489738 0.70 CA12 (0.37) TSHRALDH1A1
Dimethylformamide SCHEMBL8853072 0.69 TSHR (0.60) TSHRALDH1A1USP2ALOX15
SCHEMBL12651390 0.69 EHMT2 (0.32) TSHRALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2831177-B1 LOW VISCOSITY POLYORGANOSILOXANES COMPRISING QUATERNARY AMMONIUM GROUPS, METHODS FOR THE PRODUCTION AND THE USE THEREOF (II) MOMENTIVE PERFORMANCE MAT GMBH (DE) 2018-05-09 EP disclosed
US-5182284-A Antiasthmatic agent, antiallergen, antiinflammatory agent TAIHO PHARMACEUTICAL CO., LTD. (JP) 1993-01-26 US disclosed
EP-0465659-A1 PIPERAZINE COMPOUND, PRODUCTION THEREOF, AND MEDICINAL USE THEREOF TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1992-01-15 EP disclosed
US-4727067-A TREATMENT OF ANGINA PECTORIS, CARDIAC ARRHYTHMIA, HYPERTENSION, DEPRESSION CIBA-GEIGY CORPORATION (US) 1988-02-23 US disclosed
US-4636511-A ANTIARRHYTHMIC, HYPOTENSIVE CIBA-GEIGY AG (US) 1987-01-13 US disclosed
US-4497813-A ANTIARRHYTHMIA AGENTS, HYPOTENSIVE AGENTS, ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1985-02-05 US disclosed